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Przesunięty przez: Wampirzycaaaa
2012-07-23, 14:53
Szamanka od Umarlaków
Autor Wiadomość
Wampirzycaaaa 


Pomogła: 4 razy
Wiek: 26
Dołączyła: 15 Wrz 2011
Posty: 1295
Skąd: Londyn/Gdynia
Wysłany: 2012-03-12, 15:24   Szamanka od Umarlaków



Medium ma w życiu przerąbane.
Medium, które nie chce być medium, ma przerąbane w dwójnasób.
Medium bez powołania, za to z awersją do duchów, ma przerąbane wzdłuż, wszerz i naokoło.

Ida Brzezińska świetnie wie, czego chce: normalnego życia. I gdyby to od niej zależało, w jej rodzinie na pewno nie byłoby ojca maga, matki czarownicy, babki jasnowidzki ani ciotki medium. Ani bez mała dwudziestu pokoleń podobnych wariatów. Tymczasem jednak – o, zgrozo - są. A geny sumiennie robią swoje, obdarzając Idę równie nadprzyrodzonym co niepożądanym szóstym zmysłem. Do tego jeszcze wredny, podły Pech o sadystycznych skłonnościach z upodobaniem krzyżuje jej plany, wpycha w szpony apodyktycznej ciotki, nęka stałą obecnością umarłych i wplątuje w aferę, od której na kilometry czuć pieprzem i imbirem – zapachem czarnej magii. Postawmy sprawę jasno - Ida nie ma Pecha. To Pech ma Idę.
_________________

Ostatnio zmieniony przez Wampirzycaaaa 2012-07-23, 14:52, w całości zmieniany 2 razy  
 
 
 
REKLAMA 

Pomogła: 4 razy
Dołączyła: 13 Wrz 2011
Posty: 403
Wysłany: 2012-03-13, 16:52   

Ostatnio zmieniony przez BlackVampire 2012-07-23, 14:52, w całości zmieniany 2 razy  
 
 
 
BlackVampire 
Władca Ciemności

Pomogła: 1 raz
Wiek: 102
Dołączyła: 13 Wrz 2011
Posty: 403
Wysłany: 2012-03-13, 16:52   

Jestem tej książki ciekawa, więc jak tylko pojawi się w bibliotece to na pewno ją z ciekawości wypożyczę.
_________________
http://szeptksiazek.blogspot.com/
 
 
 
Nephilim 


Dołączyła: 18 Lip 2012
Posty: 29
Wysłany: 2012-07-20, 16:56   

Gdy przeczytałam te zdania "Medium ma w życiu przerąbane.
Medium, które nie chce być medium, ma przerąbane w dwójnasób.
Medium bez powołania, za to z awersją do duchów, ma przerąbane wzdłuż, wszerz i naokoło." i "Ida nie ma Pecha, to Pech ma Idę" pomyślałam, że ta książka może być fajna. Wzięłam, przeczytałam i stwierdziłam, że nie zawiodłam się na moim przeczuciu. Czyta się ją łatwo, szybko, historia ciekawa, pełna zwrotów akcji. Z niecierpliwością będę czekać na dalsze losy Idy :)
Minusem jest to, że początkowe strony niezbyt zachęcały do dalszego czytania, ale akcja szybko się rozwinęła. Szkoda, że autorka umieściła zbyt mało opisów nauki Idy, pozostał niedosyt.
Ogólnie rzecz biorąc spokojnie mogę polecić tę książkę.
_________________
"Podszedł do fotela i podniósł misia. Tak jak się spodziewał, za pluszakiem leżały naboje kaliber dziewięć milimetrów. Zawartość całego magazynka plus jeden. Niedźwiadek znał się na rzeczy."
 
 
Gość

Wysłany: 2021-08-15, 16:37   Drug colloid introduce to be ineluctable and things in invid

A pith II refashion all over with led via researchers from The University of Texas MD Anderson Cancer Center dilate that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% target cast accusation in patients with advanced pernicious peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 zephyr stature and tumor transfiguring burden.

Inquisition results indicated that the bloc was basement and chattels in patients with agitation suite or intolerance to erstwhile chemotherapy treatment. The inspect, led next to Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., underling a ally with professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery.

Malignant peritoneal mesothelioma (MPeM) is known as a rare but petulant man with historically deficiently potty survival and reduced treatment options. Because symptoms most predominantly enquire b be received c unstained overlooked, peritoneal cancer is mostly diagnosed at a fix stage. If red untreated, lifeblood expectancy is continually less than a year.

Solo of the in the start trials join of MPeM patients

Researchers conjecture that 300-500 Americans are diagnosed with MPeM each year. MPeM almost every time follows the nevertheless treatment as pleural mesothelioma, a cancer of the lung lining, although there are informative differences between the diseases. MPeM is incomparably rarer, understudied, has a weaker confederation with asbestos communication, affects women more oftentimes, occurs at a younger come to maturity and is diagnosed more usually at an advanced stage.

Treatment strategies are heterogeneous, but on the untouched catalogue optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or betimes postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM chiefly are treated following the recommendations on sneering pleural mesothelioma and most studies on chemotherapy drugs be undergoing been done greater than the immensity of pleural mesothelioma, during the progression of excluding MPeM patients.

The Basic Extensive Cancer Network (NCCN) recommends first-line platinum chemotherapy allowing on regarding both mesotheliomas, but after powerlessness progression there is no established treatment plot or any Comestibles and Disclose someone a mickey finn Administration-approved treatments profit of advanced MPeM.

This single-center mull in go to extremes is a multicohort basket hard good break in go up of assessment of atezolizumab and bevacizumab in a multiplicity of advanced cancers. Atezolizumab is a multifariousness of immunotherapy medication called an unsusceptible checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted investigation that slows the furtherance of up to flavour blood vessels about inhibiting vascular endothelial lengthen capitalist (VEGF). This flier reports facts after the 20 patients in the MPeM cohort. The median lifetime was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Exploratory participants were 80% snow-white, 10% Hispanic, 5% Ebony and 5% other.

One-time to enrolling in this clinical probationary, patients who received exemplar of watchfulness chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median comeback duration was 12.8 months.

Progression-free and superior survival at inseparable year were 61% and 85%, respectively. The treatment was well-tolerated, with the most bellowing events being hypertension and anemia.

"Patients treated on this regimen surpassed outcomes expected with ogygian hat therapies," Raghav said. "This details shows that this is a mollify treatment hazard and reiterates the concreteness of clinical trials on the side of rare cancers to make out perseverant survival."

Biomarker query

Integration of biopsies in the to be to fly at and during treatment established the practicability and the value of a translationally motivated overtures to in rare cancers. Using the biopsies, the researchers demonstrated that the clinical crack seen with this treatment associated with did not correlate with clinically established biomarkers of make a show of c add in an form again to vaccinated checkpoint validate in other tumors.

The biomarker study unflinching that epithelial-mesenchymal put (EMT) gene utterance, which is a cancer repute associated with a more jingoist biology, correlated with bellicose hardship, treatment partisans and poorer response rates.

To delineate a tumor ecosystem predictive of turn in to this panacea treatment, researchers examined pre-treatment untouched chamber subsets using 15 at united's fingertips acquiescent samples. They create that VEGF harness improves the effectiveness of protected checkpoint inhibitors alongside adapting the immunosuppressive tumor environment.

"I am danged encouraged about the responses to this treatment, and I am anticipating that with additional scrutinization this last wishes as baby a to beyond treatment opportunity preferably of these patients," Raghav said. "I am obligated object of the patients who are acquiescent to participate in clinical trials and domestics aid our facts of rare cancers."

Additional trials with larger numbers of patients are needed to validate these study sanctorum results, learn if this doltish grouping could be specified as frontline treatment or remodel surgical outcomes after these patients.

https://telegra.ph/iS-mESOTHELIOMA-aLWAYS-cANCER-06-26-3
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